A guideline for analyzing circadian wheel-running behavior in rodents under different lighting conditions

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Author: Jud, C
Author: Albrecht, U
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A guideline for analyzing circadian wheel-running behavior in rodents under different lighting conditions

Corinne Jud¹, Isabelle Schmutz¹, Gabriele Hampp¹, Henrik Oster² and Urs Albrecht¹^*

¹ Department of Medicine, Division of Biochemistry, University of Fribourg. 1700 Fribourg. Switzerland.
² Max-Planck-Institute for Experimental Endocrinology. 30625 Hannover. Germany.

* To whom correspondence should be addressed: Urs Albrecht, Department of Medicine, Division of Biochemistry, University of Fribourg. 1700 Fribourg. Switzerland. Phone: +41 (0)26 300 86 36. Email: urs.albrecht@unifr.ch

Biol. Proced. Online 2005;7:101-116. doi:10.1251/bpo109
Submitted: April 25, 2005; Accepted: June 20, 2005; Published: July 13, 2005.

Indexing terms: Photoperiod; Chronobiology; Circadian Rhythm; Mice.

Figure 4 Enlarged

Fig. 4:

Schematic representation of external time (ExT) in photoperiods and T-cycles. External time (ExT) subdivides any light-dark cycle into 24 units using the following formula: number of hours*24/T elapsed since the middle of the dark period. ExT0 (= ExT24) is determined as the middle of the dark period. ExT12 corresponds to the middle of the light phase. Vertical black lines indicate the corresponding external time. Black bars represent the dark period whereas the white bars correspond to lights on. (A) Schematic representation of ExT for photoperiods. (B) Schematic representation of ExT for T-cycles. ExT, external time; LD, light–dark cycle; T, period or cycle time of a Zeitgeber; h, hours.

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