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Author: Malloff, C
Author: Lam, W
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Methods Article

Two-dimensional DNA displays for comparisons of bacterial genomes

Chad Malloff1, Edie Dullaghan2, Alice Li3, Richard Stokes4, Rachel Fernandez5* and Wan Lam1

1 Departments of Pathology and Laboratory Medicine. British Columbia Cancer Research Center. Vancouver, BC. Canada.
2 Department of Pediatrics and the Division of Infectious and Immunological Diseases. British Columbia Children's Hospital. Vancouver, BC. Canada.
3 Departments of Pathology and Laboratory Medicine. The Division of Infectious and Immunological Diseases. British Columbia Children's Hospital. Vancouver, BC. Canada.
4 Departments of Pathology and Laboratory Medicine, Pediatrics, Microbiology and Immunology. University of British Columbia. The Division of Infectious and Immunological Diseases. British Columbia Children's Hospital. Vancouver, BC. Canada.
5 Microbiology and Immunology. University of British Columbia. Vancouver, BC. Canada.

* To whom correspondence should be addressed: Rachel Fernandez, Department of Microbiology & Immunology University of British Columbia. Vancouver, BC. Canada. Phone: (604) 822-6824. Fax: (604) 822-6041. Email: rachelf@interchange.ubc.ca

Biol. Proced. Online 2003;5:143-152. doi:10.1251/bpo56
Submitted: March 16, 2003; Accepted: April 01, 2003; Published: June 15, 2003.

Indexing terms: Genomics; DNA fingerprinting.


Figure 3 Enlarged

Fig. 3:

Representative Two Dimensional Bacterial Genomic Displays. (a) 2DBGD of a Sau3A I digest of B. pertussis strain 338 genomic DNA. (b) 2DBGD of a Hinf I digest of M. tuberculosis strain H37 Rv genomic DNA.

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